Development and morphology of the tentorium cerebelli

Contents

A recent study shows that the factors influencing the development and morphology of the tentorium cerebelli differ particularly between the early and mid-fetal periods.

In the early fetal period, the cerebrum covers about half of the midbrain. The separation of the dural limiting layer in the parieto-occipital region extends from the posterior cerebrum to the cranial cerebellum. The lateral folds of the tentorium cerebelli were distributed between their apex, which coincides with the falx cerebri, and their basal plane, located between the midbrain and the rostral hindbrain. The differences in the growth directions of the tentorium cerebelli components gradually decrease as the cerebrum covers the midbrain. Rotation of the tentorium cerebelli in its middle portion was demonstrated, consistent with its growth, which ceased in the mid-fetal period. The brainstem and cerebellum extend downward through differential growth, while the cerebrum covers them superiorly. The morphology of the tentorium cerebelli curved to adapt to the surfaces of the cerebellum and cerebrum. A study by Matsunari et al. (2022) suggests that the morphology of the tentorium cerebelli is influenced by factors that differ particularly between the early and mid-fetal periods. The present data from Matsunari et al. (2022) provide a much more comprehensive picture of tentorium cerebelli development depending on the fetal developmental stage than has previously been presented.   

From Matsunari et al. 2023: Axial plane of the tentorium cerebelli and the skull on MRI. The medial (red arrows), rostral, and caudolateral parts of the dural limiting layer are visible. Cp: choroid plexus; 4th: fourth ventricle; Lv: lateral ventricle; TC: tentorium cerebelli
 The following presents the timeline of morphogenesis of the embryonic and fetal brain and the tentorium cerebelli (Matsunari et al. 2023).
Morphogenesis of the embryonic and fetal brain and the tentorium cerebelli (Matsunari et al. 2023)
 Abbreviations: Cb: cerebellum; CRL: crown–rump length; CS: Carnegie stage; Cx: cerebrum; DS: dorsum sellae; FC: falx cerebri; Ib: diencephalon; iv_f: first invagination in the parieto-occipital region; Mb: midbrain; Rh: rostral hindbrain; SNL: superior nuchal line; TC: tentorium cerebelli; pCx: posterior end of the cerebrum; tTC: most cranial part of the cerebellum; bTC: point at which the posterolateral part of the TC becomes broad (here the double-layered dura mater is divided into its cranial and caudal components); cCb: the most cranial part of the cerebellum. Regarding [1] The pCx_tTC angle had a negative value. Regarding [2] The iv_f and the lateral TC appear separated and extend in different directions. Regarding [3] These phenomena were correlated. Regarding [4] Two depressions and one invagination of the TC; the orientations of the iv_f and the lateral TC appear different. Regarding [5] The pCx_cCb and bTC_cCb angles had a negative value (CRL >140 mm).  

References:

Matsunari C, Kanahashi T, Otani H, Imai H, Yamada S, Okada T, Takakuwa T. Tentorium cerebelli formation during human embryonic and early fetal development. Anat Rec (Hoboken). 2023 Mar;306(3):515-526.

Link to the study:

https://pubmed.ncbi.nlm.nih.gov/36326822/

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